Search results for "thermal [Radiation mechanisms]"

showing 10 items of 2571 documents

TRAIL acts synergistically with iron oxide nanocluster-mediated magneto- and photothermia

2019

International audience; Targeting TRAIL (Tumor necrosis factor (TNF)-Related Apoptosis-Inducing Ligand) receptors for cancer therapy remains challenging due to tumor cell resistance and poor preparations of TRAIL or its derivatives. Herein, to optimize its therapeutic use, TRAIL was grafted onto iron oxide nanoclusters (NCs) with the aim of increasing its pro-apoptotic potential through nanoparticle-mediated magnetic hyperthermia (MHT) or photothermia (PT). Methods: The nanovector, NC@TRAIL, was characterized in terms of size, grafting efficiency, and potential for MHT and PT. The therapeutic function was assessed on a TRAIL-resistant breast cancer cell line, MDA-MB-231, wild type (WT) or T…

photothermal therapyCell SurvivalMedicine (miscellaneous)TRAIL02 engineering and technologyFerric CompoundsFlow cytometryTNF-Related Apoptosis-Inducing LigandCell membrane03 medical and health sciences0302 clinical medicineMicroscopy Electron TransmissionCell surface receptorCell Line Tumormedicine[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyHumans[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biologymagnetic hyperthermiaReceptorPharmacology Toxicology and Pharmaceutics (miscellaneous)ComputingMilieux_MISCELLANEOUSchemistry.chemical_classificationCell Deathmedicine.diagnostic_testTumor Necrosis Factor-alphairon oxide nanoclustersapoptosisHyperthermia InducedFlow Cytometry021001 nanoscience & nanotechnology3. Good healthMagnetic hyperthermiamedicine.anatomical_structurechemistryTransferrinApoptosis030220 oncology & carcinogenesisCancer research[SDV.IB]Life Sciences [q-bio]/BioengineeringTumor necrosis factor alpha0210 nano-technologyResearch Paper
researchProduct

The Interconnecting Hairpin Extension "Arm": An Essential Allosteric Element of Phytochrome Activity

2023

In red-light sensing phytochromes, isomerization of the bilin chromophore triggers structural and dynamic changes across multiple domains, ultimately leading to control of the output module (OPM) activity. In between, a hairpin structure, "arm", extends from an interconnecting domain to the chromophore region. Here, by removing this protein segment in a bacteriophytochrome from Deinococcus radiodurans (DrBphP), we show that the arm is crucial for signal transduction. Crystallographic, spectroscopic, and biochemical data indicate that this variant maintains the properties of DrBphP in the resting state. Spectroscopic data also reveal that the armless systems maintain the ability to respond t…

phytochromesoluviestintäphotosensorallostery92-11histidine kinanasephotoreceptorthermal stabilityreseptorit (biokemia)87.1592-05structure and functionproteiinitvalokemia87.14 2000 MSCprotein structurePACSsignal transduction
researchProduct

Competition between chain scission and branching formation in the processing of high-density polyethylene: effect of processing parameters and of sta…

2009

Two samples of high-density polyethylene with different molecular weight were processed in a batch mixer and the rheological and structural properties were investigated. In particular, the effect of different processing parameters and the eventual presence of different stabilizers were evaluated. Actually, two reactions may occur during processing: branching/crosslinking or chain scission. The results indicate that when the processing conditions promote a scarce mobility of the macromolecular chains (lower temperatures, lower mixing speed, and higher molecular weight), branching is more favored than chain scission. On increasing the mobility of the chain (higher temperature, higher mixing s…

polyethyleneMaterials sciencePolymers and PlasticsIntrinsic viscositychain scissionConcentration effectmacromolecular substancesGeneral ChemistryPolyethyleneBranching (polymer chemistry)stabilizationchemistry.chemical_compoundSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiChemical engineeringchemistryRheologyPolymer chemistrybranchingMaterials ChemistrypolyehtyleneThermal stabilityHigh-density polyethyleneMelt flow indexdegradation
researchProduct

Analysis of a GC/MS Thermal Desorption System with Simultaneous Sniffing for Determination of Off-Odor Compounds and VOCs in Fumes Formed during Extr…

2001

A thermal desorption equipment introducing volatile organic compounds (VOCs) into the gas chromatographic/ mass spectrometric system (GC/MS) with simultaneous sniffing (SNIFF) is a suitable method for identifying the volatile organic off-odor compounds formed during the extrusion coating process of low-density polyethylene. Fumes emitted during the extrusion coating process of three different plastic materials were collected at two different temperatures (285 and 315 degrees C) from an outgoing pipe and near an extruder. The VOCs of fumes were analyzed by drawing a known volume of air through the adsorbent tube filled with a solid adsorbent (Tenax GR). The air samples were analyzed by using…

polyethylenechemistry.chemical_classificationfumesChromatographyVOCPlastics extrusionThermal desorptionTenaxExtrusion coatingcoatingsMass spectrometrymethodsAnalytical Chemistrychemistryvolatile organic compoundsVolatile organic compoundGas chromatographyGas chromatography–mass spectrometryAnalytical Chemistry
researchProduct

Comparison of the Properties of Activated Carbons Produced in One-Stage and Two-Stage Processes

2018

Activated carbons (ACs) can be produced from biomass in a thermal process either in a direct carbonization-activation process or by first carbonizing the biomass and later activating the bio-chars into activated carbons. The properties of the ACs are dependent on the type of process used for production. In this study, the properties of activated carbons produced in one-stage and two-stage processes are considered. Activated carbons were produced by physical activation of two types of starting materials: bio chars produced from spruce and birch chips in a commercial carbonization plant and from the corresponding raw chips. The activated carbons produced were characterized regarding specific …

porosity020209 energychemistry.chemical_elementBiomass02 engineering and technologyThermal treatment010501 environmental sciencesphysical activation01 natural sciencesspecific surface areaslcsh:QD241-441huokoisuuslcsh:Organic chemistryspecific surface areasBiochar0202 electrical engineering electronic engineering information engineeringmedicineactivated carbonbiomassa (teollisuus)Porosityta1160105 earth and related environmental sciencesbio-charbiomassCarbonizationOne stageGeneral MedicineaktivointichemistryChemical engineeringaktiivihiiliactivationCarbonthermal treatmentActivated carbonmedicine.drugC
researchProduct

High-affinity and selective detection of pyrophosphate in water by a resorcinarene salt receptor

2017

N-Alkyl ammonium resorcinarenes selectively bind pyrophosphate in pure water with an exceptionally high binding constant of up to 1.60 × 107 M–1, three orders of magnitude higher than ATP.

pyrophosphatereceptors010402 general chemistryMass spectrometry01 natural sciencesPyrophosphateChloridemolecular diagnosticschemistry.chemical_compoundmedicineresorcinarenesta116Biochemistry Biophysics and Structural Biologyta114010405 organic chemistryIsothermal titration calorimetryGeneral ChemistryResorcinarenePhosphateCombinatorial chemistryOrders of magnitude (mass)0104 chemical sciencesChemistrychemistrySelectivitymedicine.drug
researchProduct

Thermal bleaching of gamma-induced-defects in optical fibers

2012

International audience; Ge-doped and F-doped gamma-irradiated fibers with a maximum accumulated dose of 10 MGy were subjected to isochronal annealing treatments up to 750°C. The thermal treatment influence on the point defect generation and transformation were investigated through Radiation Induced Attenuation (RIA) changes in the visible and IR spectral domains. The thermal bleaching of gammainduced-defects depends on both temperature and composition of optical fibers.

radiationsilica fiber irradiation effects point defects thermal treatment optical measurement[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics]silicasense organsoptical measurementthermal treatmentfiber
researchProduct

Contour map of the top of the regional geothermal reservoir of Sicily (Italy).

2015

An integrated review of existing geological and geophysical data – partly acquired during oil and gas exploration – combined with new data provided by deep geothermal studies of selected key areas, was used for the 3D modeling and mapping of the top of the geothermal reservoir developed at a regional scale in Sicily (Central Mediterranean). The resulting 1:500,000 scale map covers the area of the whole Sicily (about 25,700 km2) and is devoted to represent the main input for both the thermal modeling and the evaluation of geothermal potential at a regional scale. As the map indicates the distribution at depth of a likely target for geothermal drilling, it can be also used as a rough indicato…

reservoirEarth scienceGeography Planning and Developmentcarbonatesstructural geologyexploration3D modelingGeothermal explorationcarbonateEarth and Planetary Sciences (miscellaneous)Geothermal gradientSicilyfluidgeophysicbusiness.industrygeophysicsGeothermal energyFossil fuelDrillingItalyContour linegeothermal energyScale (map)Structural geologybusinessfluidsSeismologyGeology
researchProduct

Measuring phenotypes in fluctuating environments

2020

Despite considerable theoretical interest in how the evolution of phenotypic plasticity should be shaped by environmental variability and stochasticity, how individuals actually respond to these aspects of the environment within their own lifetimes remains unclear. We propose that this understanding has been hampered by experimental approaches that expose organisms to fluctuating environments (typically treatments where fluctuations in the environment are cyclical vs. erratic) for a pre‐determined duration, while ensuring that the mean environment over that the entire exposure period is invariable. This approach implicitly assumes that responses to the mean and variance/predictability in th…

reversible plasticitylämmönsietofungiunpredictable environmentsvesikirputheat tolerancefenotyyppivaihtelulämpötilabet-hedgingthermal toleranceympäristönmuutoksetinsurance
researchProduct

Acclimation capacity and rate change through life in the zooplankton Daphnia

2020

When a change in the environment occurs, organisms can maintain an optimal phenotypic state via plastic, reversible changes to their phenotypes. These adjustments, when occurring within a generation, are described as the process of acclimation. While acclimation has been studied for more than half a century, global environmental change has stimulated renewed interest in quantifying variation in the rate and capacity with which this process occurs, particularly among ectothermic organisms. Yet, despite the likely ecological importance of acclimation capacity and rate, how these traits change throughout life among members of the same species is largely unstudied. Here we investigate these rel…

reversible plasticitysopeutuminenakklimatisaatiolämmönsietoallometryvesikirputheat tolerancefenotyyppibody sizethermal toleranceympäristönmuutokset
researchProduct